About
Professor Topeli is a full time intensivist and the Director of the Medical Intensive Care Unit in the first and the only accredited ICU by the European Board of Intensive Care Medicine in Turkey. Since January 2012, she has also been the Director of the Adult Hospital of Hacettepe University Hospitals in Ankara. Professor Topeli worked as a fellow with Prof. Dr. Martin Tobin in Loyola University at Chicago, Division of Pulmonary and Critical Care Medicine from 1996 to 1998. She received American Thoracic Society young investigator award in 2000 and European Respiratory Society COPD local research award in 2001. Professor Topeli is a founding member of Turkish Society of Medical and Surgical Intensive Care Medicine which was established in 2005. She was the first president of the society and assisted in the organization of 10 National, 8 regional and 2 International Meetings. Since 2013, she has been elected as a council member of the World Federation of Societies of Intensive and Critical Care Medicine. She is the Chief Editor of the Journal of Medical and Surgical Intensive Care Medicine, has given more than 100 lectures and is the author of more than 80 scientific manuscripts and book chapters.
Обучение
- 1998Yoğun BakımYoğun Bakım
- 1996İç Hastalıklarıİç Hastalıkları
- 2012PhD — Yoğun Bakım Uzmanlığı Denkliği
- 1991Tıp Fakültesi (İngilizce)Hacettepe Üniversitesi
- 1985TED Ankara Koleji
Expertise
Publications
Source: Hacettepe University academic database (AVESİS) · All publications (163) ↗
Articles 132
- Exploring the genetic landscape of COVID-19 susceptibility and severity among patients in TürkiyeBMC Medical Genomics, cilt.19, sa.1, 2026 (SCI-Expanded, Scopus)
- Diagnostic errors in critically ill patients: challenges, contributing factors, and improvement strategies through the SEIPS frameworkIntensive Care Medicine, cilt.52, sa.10, ss.2220-2223, 2026 (SCI-Expanded, Scopus)
- Clinical criteria for the definition of refractory septic shock: a joint Delphi consensus from the Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM)Intensive Care Medicine, cilt.52, sa.5, ss.984-1000, 2026 (SCI-Expanded, Scopus)
- Society of Critical Care Medicine Guidelines for the Administration of Neuromuscular Blockade in Adults With Acute Respiratory Distress SyndromeCritical care medicine, cilt.54, sa.3, ss.634-643, 2026 (SCI-Expanded, Scopus)
- Executive Summary: Society of Critical Care Medicine Guidelines for the Administration of Neuromuscular Blockade in Adults With Acute Respiratory Distress SyndromeCritical care medicine, cilt.54, sa.3, ss.630-633, 2026 (SCI-Expanded, Scopus)
- Training for humanization in intensive care: a competency-based educational continuum for patient- and family-centred practiceIntensive Care Medicine, 2026 (SCI-Expanded, Scopus)
- Omega-3–rich fish oil lipid emulsions prevent sepsis-driven mesenteric hypoperfusion and multiorgan injury in a murine modelTurkish Journal of Medical Sciences, cilt.56, sa.3, ss.897-906, 2026 (SCI-Expanded, Scopus, TRDizin)
- Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational studyBMC INFECTIOUS DISEASES, cilt.25, sa.1, 2025 (SCI-Expanded, Scopus)
- Evaluation of the clinical characteristics and outcomes of patients admitted to intensive care units after the Kahramanmaras (Türkiye) earthquake: a multicenter observational studyFRONTIERS IN MEDICINE, cilt.12, 2025 (SCI-Expanded, Scopus)
- HYPOPHOSPHATEMIA: UNRAVELING A LETHAL CONNECTION WITH ICU MORTALITY IN CRITICALLY ILL COVID-19 PATIENTS: A MULTICENTER OBSERVATIONAL STUDYJOURNAL OF MEDICAL BIOCHEMISTRY, cilt.44, sa.2, ss.330-338, 2025 (SCI-Expanded, Scopus)
- Practice of oxygen administration in patients hospitalized in internal medicine wards and intensive care units: A single-center prospective, observational studySAO PAULO MEDICAL JOURNAL, cilt.143, sa.3, 2025 (SCI-Expanded, Scopus)
- Multimodal data fusion using sparse canonical correlation analysis and cooperative learning: a COVID-19 cohort studyNPJ DIGITAL MEDICINE, cilt.7, sa.1, 2024 (SCI-Expanded, Scopus)
- The INTOXICATE study: methodology and preliminary results of a prospective observational studyCRITICAL CARE, cilt.28, sa.1, 2024 (SCI-Expanded, Scopus)
- Effect of therapeutic plasma exchange on antimicrobials in critically ill patientsCRITICAL CARE, cilt.28, sa.1, 2024 (SCI-Expanded, Scopus)
- Parenteral nutrition consensus report from KEPANNutrition, cilt.123, 2024 (SCI-Expanded, Scopus)
- Lomentospora prolificans Fungemia in a Patient With T-Cell Large Granular Leukemia: A Rare Pathogen in TürkiyeMIKROBIYOLOJI BULTENI, cilt.58, sa.2, ss.209-216, 2024 (SCI-Expanded, Scopus, TRDizin)
- Chronic critical illness in critically ill COVID-19 patientsChronic Illness, cilt.20, sa.1, ss.86-95, 2024 (SCI-Expanded, SSCI, Scopus)
- Effect of Awake Prone Positioning on ROX Index in Critically-ill Patients With Respiratory Failure due to COVID-19JOURNAL OF INTENSIVE CARE MEDICINE, sa.12, ss.1158-1164, 2023 (SCI-Expanded, Scopus)
- Nutritional practices in medical intensive care units: Multicenter, one-day point prevalence study Pratiques nutritionnelles dans les unités de soins intensifs médicaux : étude de prévalence ponctuelle multicentrique sur une journéeNutrition Clinique et Metabolisme, cilt.37, sa.4, ss.221-226, 2023 (SCI-Expanded, Scopus)
- Evaluation of whole blood thiamine pyrophosphate concentrations in critically ill patients receiving chronic diuretic therapy prior to admission to Turkish intensive care units: A pragmatic, multicenter, prospective studyJournal of Critical Care, cilt.77, 2023 (SCI-Expanded, Scopus)
- Comparison of laser speckle contrast imaging with laser Doppler perfusion imaging for tissue perfusion measurementMicrocirculation, cilt.30, sa.1, 2023 (SCI-Expanded, Scopus)
- Follow-up of Patients Receiving Home Parenteral Nutrition With a Competent Home Infusion Nurse Decreases the Prevalence of Catheter InfectionsTopics in Clinical Nutrition, cilt.38, sa.1, ss.28-35, 2023 (SCI-Expanded, Scopus)
- Polymyxin B-related neurotoxicity: a brief case reportEuropean Journal of Hospital Pharmacy, 2023 (SCI-Expanded, Scopus)
- Comparison of Cumulative Corticosteroid Doses for Critically Ill Patients with COVID-19MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, 2023 (ESCI)
- Assessment of Admission COVID-19 Associated Hyperinflammation Syndrome Score in Critically-Ill COVID-19 PatientsJOURNAL OF INTENSIVE CARE MEDICINE, cilt.38, sa.1, ss.70-77, 2023 (SCI-Expanded, Scopus)
- The Significance of Systemic Immune-Inflammatory Index and Platelet-Neutrophil Ratio on Early Mortality in Septic Shock Patients and their Association with Vitamin D and Parathyroid Hormone RatioActa Medica, cilt.53, sa.4, ss.384-393, 2022 (TRDizin)
- The Use of High-Flow Nasal Oxygen Therapy in the Management of Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Feasibility StudyTURKISH THORACIC JOURNAL, cilt.23, sa.5, ss.336-342, 2022 (ESCI, Scopus)
- The impact of COVID-19 pandemic on nosocomial multidrug-resistant bacterial bloodstream infections and antibiotic consumption in a tertiary care hospitalGMS HYGIENE AND INFECTION CONTROL, cilt.17, 2022 (ESCI)
- A screening study for COVID-19-associated pulmonary aspergillosis in critically ill patients during the third wave of the pandemicMYCOSES, cilt.65, ss.724-732, 2022 (SCI-Expanded, Scopus)
- Association of chronic heart failure with mortality in old intensive care patients suffering from Covid-19ESC HEART FAILURE, cilt.9, ss.1756-1765, 2022 (SCI-Expanded, Scopus)
- Predictive role of pretest probability scores and risk factors of contrast-induced acute kidney injury in patients who underwent CT pulmonary angiography for the suspicion of pulmonary embolismEURASIAN JOURNAL OF PULMONOLOGY, cilt.24, sa.2, ss.130-139, 2022 (ESCI, TRDizin)
- Comparison of critically ill COVID-19 and influenza patients with acute respiratory failureACUTE AND CRITICAL CARE, cilt.37, sa.2, ss.168-176, 2022 (ESCI, Scopus)
- Tocilizumab treatment in severe COVID-19: a multicenter retrospective study with matched controlsRHEUMATOLOGY INTERNATIONAL, cilt.42, sa.3, ss.457-467, 2022 (SCI-Expanded, Scopus)
- Neurological complications during the course of severe COVID-19: is it just the tip of the iceberg?ACUTE AND CRITICAL CARE, cilt.37, sa.1, ss.124-126, 2022 (ESCI, Scopus)
- Persistence of Abnormal Inflammatory and Coagulation Laboratory Tests in Critically-ill COVID-19 Survivors: Case SeriesJOURNAL OF CRITICAL & INTENSIVE CARE, cilt.13, ss.1-7, 2022 (ESCI, Scopus, TRDizin)
- Effects of end-expiratory lung volume versus PaO2 guided PEEP determination on respiratory mechanics and oxygenation in moderate to severe ARDSExperimental Lung Research, cilt.48, sa.1, ss.12-22, 2022 (SCI-Expanded, Scopus)
- Blood Level Monitoring of Antimicrobial Drugs in Intensive Care PatientsFLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, cilt.27, sa.1, ss.1-10, 2022 (ESCI, TRDizin)
- Diversity of intensive care specialists and fellows-in-training in TurkeyCANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, cilt.68, sa.12, ss.1833-1835, 2021 (SCI-Expanded, Scopus)
- AI-Based Quantitative CT Analysis of Temporal Changes According to Disease Severity in COVID-19 PneumoniaJOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, cilt.45, sa.6, ss.970-978, 2021 (SCI-Expanded, Scopus)
- Salbutamol Delivered by Jet Nebulizer: Closed System Design and Impact of a Model BiofilmRESPIRATORY CARE, cilt.66, sa.9, ss.1440-1445, 2021 (SCI-Expanded, Scopus)
- Clinical Outcomes and Independent Risk Factors for 90-Day Mortality in Critically Ill Patients with Respiratory Failure Infected with SARS-CoV-2: A Multicenter Study in Turkish Intensive Care UnitsBALKAN MEDICAL JOURNAL, cilt.38, sa.5, ss.296-305, 2021 (SCI-Expanded, Scopus, TRDizin)
- Association of baseline diaphragm, rectus femoris and vastus intermedius muscle thickness with weaning from mechanical ventilationRESPIRATORY MEDICINE, cilt.185, 2021 (SCI-Expanded, Scopus)
- Cardio-Pulmonary-Renal Consequences of Severe COVID-19CARDIORENAL MEDICINE, sa.3, ss.133-139, 2021 (SCI-Expanded, Scopus)
- Evaluation of the blue code system established in the health campus of a university hospitalTURKISH JOURNAL OF EMERGENCY MEDICINE, cilt.21, sa.1, ss.14-19, 2021 (ESCI, Scopus, TRDizin)
- Is COVID-19 a risk factor for invasive pulmonary aspergillosis in critically ill patients?TUBERKULOZ VE TORAKS-TUBERCULOSIS AND THORAX, cilt.69, sa.1, ss.118-120, 2021 (ESCI, Scopus, TRDizin)
- FUNCTIONAL INDEPENDENCE AND MUSCLE STRENGTH IN PATIENTS WITH ACUTE RESPIRATORY FAILURE WITH AND WITHOUT NON-INVASIVE MECHANICAL VENTILATION SUPPORTTurkish Journal of Physiotherapy and Rehabilitation, cilt.31, sa.3, ss.247-254, 2020 (ESCI, Scopus, TRDizin)
- Visual and software-based quantitative chest CT assessment of COVID-19: correlation with clinical findingsDIAGNOSTIC AND INTERVENTIONAL RADIOLOGY, cilt.26, sa.6, ss.557-564, 2020 (SCI-Expanded, Scopus, TRDizin)
- Maternal Mortality: 10 Year Experience of a Tertiary Center in TurkeyCASE REPORTS IN MEDICINE, cilt.2020, 2020 (ESCI, Scopus)
- In Search for the Ideal Risk Score in Sepsis.American journal of respiratory and critical care medicine, cilt.202, ss.152-153, 2020 (SCI-Expanded, Scopus)
- Critically-ill COVID-19 patient.Turkish journal of medical sciences, cilt.50, ss.585-591, 2020 (SCI-Expanded, Scopus, TRDizin)
- Value of Prognostic Scores in Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis Patients in Intensive Care Unit: A Multicenter Retrospective Cohort Study from TurkeyTurkish journal of medical sciences, cilt.50, ss.1223-1230, 2020 (SCI-Expanded, Scopus, TRDizin)
- Enfeksiyon şüphesi ile iç hastalıkları yoğunbakım ünitelerine yatan hastalarda erkenuyarı ve sepsis skorları ile mortalite ilişkisinindeğerlendirilmesiJournal of Medical and Surgical Intensive Care, 2019 (TRDizin)
- Infections in the Elderly Critically-Ill Patients.Frontiers in medicine, cilt.6, ss.118, 2019 (SCI-Expanded, Scopus)
- The effect of the first-year residents orientation period on intensive care and hospital mortality, in a medical intensive care unit, within a developing country.Journal of critical care, cilt.51, ss.105-110, 2019 (SCI-Expanded, Scopus)
- Approach to Nutritional Therapy in Patients Who Require Vasopressors General Information and Protocol ProposalJOURNAL OF MEDICAL AND SURGICAL INTENSIVE CARE MEDICINE, cilt.10, sa.1, ss.31-34, 2019 (ESCI, Scopus, TRDizin)
- Characteristics of obstetric admissions to intensive care unit: APACHE II, SOFA and the Glasgow Coma ScaleJournal of Perinatal Medicine, 2019 (SCI-Expanded, Scopus)
- Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patientsTurkish Journal of Medical Sciences, cilt.49, sa.2, ss.543-550, 2019 (SCI-Expanded, Scopus, TRDizin)
- İN VİTRO ACİNETOBACTER BAUMANİİ BİYOFİLMTABAKASI OLAN VE OLMAYAN ENDOTRAKEALTÜP VE ISI NEM DEĞİŞTİRİCİ FİLTREDE İNHALERSALBUTAMOL İLAÇ BİRİKİM DÜZEYİNİNÖLÇÜMÜYoğun Bakım Derg, 2018 (TRDizin)
- Current Statement of Intensive Care Units in Turkey: Data obtained from 67 Centers.Turkish thoracic journal, cilt.19, ss.209-215, 2018 (ESCI, Scopus, TRDizin)
- Sequential vitamin D and parathyroid hormone measurement in patients with septic shock: Could they be prognostic marker in septic shockExperimental Biomedical Research, cilt.1, sa.3, ss.90-102, 2018 (Hakemli Dergi)
Conference papers 28
- INVAZIV MEKANIK VENTILASYON UYGULANAN HASTALARDA MEKANIK VENTILASYONDAN AYRILMA SÜRECINI ÖNGÖRMEDE DIYAFRAM ULTRASONOGRAFISININ YERITurkish Thoracic Society, 23rd Annual Congress, 15 - 18 Ekim 2020, (Tam Metin Bildiri)
- Enfeksiyon şüph esi ile iç hastalıkları yoğunbakım ünitelerine yatan hastalarda erkenuyarı ve sepsis skorları ile mortalite ilişkisinindeğerlendirilmesi16. ULUSAL TÜRK DAHİLİ VE CERRAHİ BİLİMLER YOĞUN BAKIM KONGRESİ, Türkiye, 8 - 11 Kasım 2019, (Tam Metin Bildiri)
- The relationship between Parenteral Nutrition at home and quality of life and catheter infections41. ESPEN CONGRESS on clinical nutrition and metabolism, 31 Ağustos - 03 Eylül 2019, (Tam Metin Bildiri)
- in vitro acinetobacter baumanii biyofilm tabakası olan ve olmayan endotrakeal tüp ve ısı nem değiştirici filtrede inhaler salbutamol ilaç birikim düzeyinin ölçümü15. DAHİLİ CERRAHİ BİLİMLER - 7.AVRASYA YOĞUN BAKIM KONGRESİ, 21 - 24 Kasım 2018, (Tam Metin Bildiri)
- Evaluation of patients with the diagnosis of vasculitis admitted to a medical ICULIVES, 2018, 20 - 24 Ekim 2018, (Özet Bildiri)
- Outcome of adults with cystic fibrosis admitted to the medical intensive care unitECFS Conference, 2018, 6 - 09 Haziran 2018, (Özet Bildiri)
- NSAİİ kullanımına bağlı renal tübülopatinin eşlik ettiği normal anyon açıklı DKA ve Geçici bilateral işitme kaybı olgusu19. ULUSAL İÇ HASTALIKLARI KONGRESİ, Antalya, Türkiye, 11 - 15 Ekim 2017, (Özet Bildiri)
- Evaluation of Antibiotics Drug İnteraction in Intensive Care Unit45th ESCP Annual Symposium Clinical pharmacy tackling inequalities and access to health care, Norveç, 5 - 07 Ekim 2016, (Özet Bildiri)
- Evaluation of Antibiotic Drug Interactions in Intensive Care Unit45.European Symposium on Clinical Pharmacy, Oslo, Norveç, 5 - 07 Ekim 2016, cilt.39, ss.290-291, (Özet Bildiri)
- Influence of the Clinical Pharmacy Postgraduate Program Students in Intensive Care Unit45TH ESCP ANNUAL SYMPOSIUM CLINICAL PHARMACY, 5 - 07 Ekim 2016, (Özet Bildiri)
- Drug Drug Interactions of Antibiotics and Other Drugs in Intensive Care Unit45TH ESCP ANNUAL SYMPOSIUM CLINICAL PHARMACY, 5 - 07 Ekim 2016, (Özet Bildiri)
- Akut Böbrek Hasarı Gelişim Zamanının Kritik Hastalarda Mortalite Üzerine Etkisi: Yoğun bakımda kazanılmış akut böbrek hasarı yeni bir terminoloji mi?18. ULUSAL HİPERTANSİYON VE BÖBREK HASTALIKLARI KONGRESİ, Girne, Kıbrıs (Kktc), 12 - 15 Mayıs 2016, (Özet Bildiri)
- Klinik Eczacılık Lisansüstü Eğitim Programı Öğrencileri Tarafından Yoğun Bakım Ünitesinde Yürütülen Klinik Eczacılık Uygulamalarının Etkinliğinin Değerlendirilmesi13. ULUSAL DAHİLİ VE CERRAHİ BİLİMLER YOĞUN BAKIM KONGRESİ, Türkiye, 2 - 05 Kasım 2016, (Özet Bildiri)
- Yoğun Bakım Hastalarında Antibiyotiklerin Diğer İlaçlarla Etkileşimlerinin DeğerlendirilmesiHastane İnfeksiyonları Kongresi 2016, Türkiye, 30 Mart - 03 Nisan 2016, (Özet Bildiri)
- Bed side post pyloric tube placement: Analysis of 300 patientsESPEN CONGRESS 2006, 19 - 22 Ekim 2006, (Tam Metin Bildiri)
- Evaluation of predictive ability of the APACHEII system in a Turkish medical intensive care unitThe 17th IEA World Congress of Epdiemiology, Bangkok, Tayland, 21 - 25 Ağustos 2005, ss.205, (Özet Bildiri)
- Does Glycemic Variability Affect Development of Chronic Critical Illness and Mortality in the Intensive Care Unit?
- YOĞUN BAKIM HASTALARINDA NRS 2002, NUTRIC, GLIM SKORLARI ILE MALNÜTRISYON DEĞERLENDIRILMESI VE KLINIK SONLANIMA ETKILERININ BELIRLENMESI
- YOĞUN BAKIM HASTALARINDA NRS 2002, NUTRİC, GLİM SKORLARI ILE MALNÜTRISYON DEĞERLENDIRILMESI VE KLINIK SONLANIMA ETKILERININ BELIRLENMESI
- COVID-19 PANDEMISININ ILK ÜÇ DALGASININ KARŞILAŞTIRILMASI: HACETTEPE ÜNIVERSITESI IÇ HASTALIKLARI YOĞUN BAKIM DENEYIMI
- Chronic Critical Illness Among COVID‑19 Patients Admitted to Intensive Care Unit
- Is COVID-19 a risk factor for invasive pulmonary aspergillosis in critically ill patients?
- COVID-19 YOĞUN BAKIM HASTALARINDA INVAZIV PULMONER ASPERGILLOZIS IÇIN BIR RISK FAKTÖRÜ MÜDÜR?
- Is obesity paradox real or not? The role of leptin in septic shock patients
- Pulmonary artery to aorta ratio is correlated with pulmonary artery pressure but not with mortality in critically ill COPD patients
- Vaka Raporu: Akciğer Metastazını Taklit Eden İnfeksiyöz Orjinli Nodüler Görünüm
- Transfüzyon ilişkili graft versus host hastalığı
- Measles in adults Clinical syndrome and treatment strategies
Kitaplar 3
- Sepsiste Vazoaktif İlaç TedavileriSEPSİS Patofizyolojiden Tedaviye, TOPELİ İSKİT ARZU, Editör, Hipokrat, Ankara, ss.239-258, 2024
- Management of Crush SyndromeClinical Cases in Intensive Care Unit, Arzu Topeli, Gene Sung, Jorge Hidalgo, Editör, Editorial Distribuna, Mexico City, ss.83-100, 2023
- Yoğun Bakımda Yaşam Sonu KararlarıKlinik Etik Kültürel ve Hukuki Yönleriyle Yaşamın Sonuna İlişkin Kararlar, Prof. Dr. Nükhet Büken Örnek, Öğr. Gör. Dr. Aslıhan Akpınar, Editör, Hacettepe Üniversitesi Matbaası, Ankara, ss.29-38, 2014
Контакты
- Phone
- 0312 305 11 03
- Department
- Internal Medicine Intensive Care, Больница для взрослых
- Languages
- English
Последнее обновление:
