About
Sevim Erdem Özdamar received her MD degree from Hacettepe University School of Medicine, Ankara Turkey. In 1989. She then continued her training as a resident first in Gazi University Department of Neurology then in Hacettepe University Department of Neurology. After completing her residency she continued her training on neuromuscular diseases as a research fellow in Ohio State University Department of Neurology in 1996-1997. She especially worked on interpretation of nevre and muscle biopsies. She took up a position in Hacettepe University Department of Neurology as a university lecturer in 1998. She currently holds a position as a Professor in the same Department and she is stil the head of the department.
Dr. Erdem Özdamar has a long-standing interest in every aspect of neuromuscular disorders especially interested in immune –mediated neuropathies and painful neuropathies. She received Hacettepe University 2003-2004 promoting science award for her studies on neuromuscular diseases. She has co-authored 43 peer-reviewed publications in international journals.
Education
- Nöropatik AğrıAlgoloji
- Nöromusküler HastalıklarNöroloji
- MSc — NörolojiHacettepe
- 1989TıpHacettepe
- 1983TED Ankara Koleji
Expertise
Publications
Source: Hacettepe University academic database (AVESİS) · All publications (102) ↗
Articles 64
- Increased epidermal growth factor expression in amyotrophic lateral sclerosis patients: A potential protective mechanism against pressure ulcersTurk Noroloji Dergisi, cilt.32, sa.3, ss.230-236, 2026 (ESCI, Scopus)
- Detection of inflammation and glial cell-related biomarkers in adults with spinal muscular atrophy receiving nusinersen therapyNeurological Sciences, cilt.47, sa.1, 2026 (SCI-Expanded, Scopus)
- Random X chromosome inactivation in female Charcot-Marie-Tooth disease type X1: insights from sural nerve biopsy analysisBMC NEUROLOGY, cilt.25, sa.1, 2025 (SCI-Expanded, Scopus)
- Effect of Follicular T Helper and T Helper 17 Cells-Related Molecules on Disease Severity in Patients with Myasthenia GravisEUROPEAN NEUROLOGY, cilt.87, sa.5-6, ss.223-229, 2024 (SCI-Expanded, Scopus)
- Clinical and laboratory remission with rituximab in anti-MuSK-positive myasthenia gravisIRISH JOURNAL OF MEDICAL SCIENCE, cilt.193, ss.2989-2994, 2024 (SCI-Expanded, Scopus)
- Home infusion experience in patients with Pompe disease receiving avalglucosidase alfa during three clinical trialsMOLECULAR GENETICS AND METABOLISM, cilt.143, sa.4, 2024 (SCI-Expanded, Scopus)
- A novel pathogenic PTRH2 variant indicates seizure association with protein-truncating variants in Infantile-Onset Multisystem Neurologic, Endocrine and Pancreatic Disease (IMNEPD)EUROPEAN JOURNAL OF HUMAN GENETICS, ss.1494, 2024 (SCI-Expanded, Scopus)
- A novel pathogenic PTRH2 variant indicates seizure association with protein-truncating variants in Infantile-Onset Multisystem Neurologic, Endocrine and Pancreatic Disease (IMNEPD)EUROPEAN JOURNAL OF HUMAN GENETICS, ss.1494, 2024 (SCI-Expanded, Scopus)
- Differentiating recurrent Guillain-Barre syndrome and acute-onset chronic inflammatory polyneuropathy: literature reviewACTA NEUROLOGICA BELGICA, cilt.124, ss.1467-1475, 2024 (SCI-Expanded, Scopus)
- VARIABLE PHENOTYPE IN FEMALES WITH HETEROZYGOUS GJB1 MUTATIONJOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2024 (SCI-Expanded, Scopus)
- Recurrent simultaneous central nervous system demyelination with possible peripheral demyelination / nodopathy in a seronegative patientIDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE, cilt.77, sa.9-10, ss.357-360, 2024 (SCI-Expanded, Scopus)
- Nusinersen for adults with spinal muscular atrophyNeurological Sciences, cilt.44, sa.7, ss.2393-2400, 2023 (SCI-Expanded, Scopus)
- Efficacy and Safety of Avalglucosidase Alfa in Patients with Late-Onset Pompe Disease after 97 Weeks: A Phase 3 Randomized Clinical TrialJAMA Neurology, cilt.80, sa.6, ss.558-567, 2023 (SCI-Expanded, Scopus)
- The evaluation of small fibers in multiple sclerosisMultiple Sclerosis and Related Disorders, cilt.72, 2023 (SCI-Expanded, Scopus)
- Expert opinion on the diagnostic odyssey and management of late-onset Pompe disease: a neurologist's perspectiveFrontiers in Neurology, cilt.14, 2023 (SCI-Expanded, Scopus)
- Efficacy and safety of Avalglucosidase Alfa in participants with late-onset Pompe Disease after 145 weeks' treatment during the COMET trialNEUROMUSCULAR DISORDERS, cilt.32, 2022 (SCI-Expanded, Scopus)
- COMET: Efficacy and safety of avalglucosidase alfa in late-onset Pompe disease participants after 97 weeks of treatmentEUROPEAN JOURNAL OF NEUROLOGY, cilt.29, ss.59-60, 2022 (SCI-Expanded, Scopus)
- Home-infusion experience in patients with Pompe disease receiving avalglucosidase alfa during three clinical trials (COMET, NEO-EXT, and Mini-COMET)MOLECULAR GENETICS AND METABOLISM, cilt.135, sa.2, 2022 (SCI-Expanded, Scopus)
- The avalglucosidase alfa phase 3 COMET trial in late-onset Pompe disease patients: Efficacy and safety results after 97 weeksMOLECULAR GENETICS AND METABOLISM, cilt.135, sa.2, 2022 (SCI-Expanded, Scopus)
- Efficacy and safety results of the avalglucosidase alfa phase 3 COMET trial in late-onset Pompe disease patientsMOLECULAR GENETICS AND METABOLISM, cilt.132, sa.2, 2021 (SCI-Expanded, Scopus)
- Comprehensive clinical, biochemical, radiological and genetic analysis of 28 Turkish cases with suspected metachromatic leukodystrophy and their relativesMOLECULAR GENETICS AND METABOLISM REPORTS, cilt.25, 2020 (SCI-Expanded, Scopus)
- Laboratory diagnosis of metachromatic leukodystrophy requires more than arylsulfatase A assayFEBS OPEN BIO, cilt.9, ss.199, 2019 (SCI-Expanded, Scopus)
- Novel SBF2 mutations and clinical spectrum of Charcot-Marie-Tooth neuropathy type 4B2CLINICAL GENETICS, cilt.94, sa.5, ss.467-472, 2018 (SCI-Expanded, Scopus)
- Establishment of primary myoblast cell cultures from cryopreserved skeletal muscle biopsies to serve as a tool in related research & development studiesJOURNAL OF THE NEUROLOGICAL SCIENCES, cilt.393, ss.100-104, 2018 (SCI-Expanded, Scopus)
- Do Perineuronal Net Elements Contribute to Pathophysiology of Spinal Muscular Atrophy? In Vitro and Transcriptomics InsightsOMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, cilt.22, sa.9, ss.598-606, 2018 (SCI-Expanded, Scopus)
- The histopathological evaluation of small fiber neuropathy in patients with vitamin B12 deficiencyACTA NEUROLOGICA BELGICA, cilt.118, sa.3, ss.405-410, 2018 (SCI-Expanded, Scopus)
- Ocular surface alterations and in vivo confocal microscopic characteristics of corneas in patients with myasthenia gravisEUROPEAN JOURNAL OF OPHTHALMOLOGY, cilt.28, sa.5, ss.541-546, 2018 (SCI-Expanded, Scopus)
- A rare cause of proximal muscle weakness: immune necrotising myopathySCOTTISH MEDICAL JOURNAL, cilt.63, sa.3, ss.82-86, 2018 (SCI-Expanded, Scopus)
- A database for screening and registering late onset Pompe disease in TurkeyNEUROMUSCULAR DISORDERS, cilt.28, sa.3, ss.262-267, 2018 (SCI-Expanded, Scopus)
- The altered expression of perineuronal net elements during neural differentiationCELLULAR & MOLECULAR BIOLOGY LETTERS, cilt.23, 2018 (SCI-Expanded, Scopus)
- Recent therapeutic developments in spinal muscular atrophyTURKISH JOURNAL OF MEDICAL SCIENCES, cilt.48, sa.2, ss.203-211, 2018 (SCI-Expanded, Scopus, TRDizin)
- Myophosphorylase (PYGM) mutations determined by next generation sequencing in a cohort from Turkey with McArdle diseaseNEUROMUSCULAR DISORDERS, cilt.27, sa.11, ss.997-1008, 2017 (SCI-Expanded, Scopus)
- New mutations and genotype-phenotype correlation in late-onset Pompe patientsACTA NEUROLOGICA BELGICA, cilt.117, sa.1, ss.269-275, 2017 (SCI-Expanded, Scopus)
- Transcript levels of plastin 3 and neuritin 1 modifier genes in spinal muscular atrophy siblingsPEDIATRICS INTERNATIONAL, cilt.59, sa.1, ss.53-56, 2017 (SCI-Expanded, Scopus)
- Dysferlinopathy: A Case Report and Literature UpdateISTANBUL MEDICAL JOURNAL, cilt.17, sa.4, ss.136-140, 2016 (ESCI, TRDizin)
- The evaluation of small fibres in asymptomatic patients with Val30Met mutationEUROPEAN JOURNAL OF NEUROLOGY, cilt.23, ss.231, 2016 (SCI-Expanded, Scopus)
- Autoimmune stormEUROPEAN JOURNAL OF NEUROLOGY, cilt.23, ss.437, 2016 (SCI-Expanded, Scopus)
- Spinal muscular atrophy type III: Molecular genetic characterization of Turkish patientsEUROPEAN JOURNAL OF MEDICAL GENETICS, cilt.58, sa.12, ss.654-658, 2015 (SCI-Expanded, Scopus)
- Three Turkish families with different transthyretin mutationsNEUROMUSCULAR DISORDERS, cilt.25, sa.9, ss.686-692, 2015 (SCI-Expanded, Scopus)
- Proinflammatory effect of AbetaPP induced ST6GAL1 secretion from C2C12 myogenic cell lineTURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.40, sa.1, ss.31-36, 2015 (SCI-Expanded, Scopus, TRDizin)
- Unraveling the genetic landscape of autosomal recessive Charcot-Marie-Tooth neuropathies using a homozygosity mapping approachNEUROGENETICS, cilt.16, sa.1, ss.33-42, 2015 (SCI-Expanded, Scopus)
- REMISSION WITH FINGOLIMOD IN A CASE OF DEMYELINATING POLYNEUROPATHYMUSCLE & NERVE, cilt.50, sa.4, ss.615-617, 2014 (SCI-Expanded, Scopus)
- The Course of Myasthenia Gravis with Systemic Lupus ErythematosusEUROPEAN NEUROLOGY, cilt.72, ss.326-329, 2014 (SCI-Expanded, Scopus)
- A novel desmin mutation leading to autosomal recessive limb-girdle muscular dystrophy: distinct histopathological outcomes compared with desminopathiesJOURNAL OF MEDICAL GENETICS, cilt.50, sa.7, ss.437-443, 2013 (SCI-Expanded, Scopus)
- Myasthenia Gravis; Single Entity, Variable Clinical Features: Ten Years of Clinical Experience in a Tertiary Care Center Ten Years Clinical Experience of a Tertiary Care CenterJOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.30, sa.1, ss.135-143, 2013 (SCI-Expanded, Scopus, TRDizin)
- Identification of a Novel Twinkle Mutation in a Family With Infantile Onset Spinocerebellar Ataxia by Whole Exome SequencingPEDIATRIC NEUROLOGY, cilt.46, sa.3, ss.172-177, 2012 (SCI-Expanded, Scopus)
- Diabetic muscular infarct: an unusual cause of extremity pain and dysfunctionRHEUMATOLOGY INTERNATIONAL, cilt.32, sa.2, ss.525-528, 2012 (SCI-Expanded, Scopus)
- Overexpression of amyloid beta precursor protein enhances expression and secretion of ST6Gal1 in C2C12 myogenic cell lineCELL BIOLOGY INTERNATIONAL, cilt.35, sa.1, ss.9-13, 2011 (SCI-Expanded, Scopus)
- Early Diagnosis of Distal Peripheral Polyneuropathy Due to Glucose Metabolism Disorders via Intraepidermal Nerve Fiber AnalysisTURKISH JOURNAL OF NEUROLOGY, cilt.15, sa.1, ss.24-30, 2009 (ESCI, TRDizin)
- Nuclear morphometric analysis in gastrointestinal stromal tumors: A preliminary studyTURKISH JOURNAL OF GASTROENTEROLOGY, cilt.18, sa.2, ss.71-76, 2007 (SCI-Expanded, Scopus, TRDizin)
- Calpain-3 mutations in TurkeyEUROPEAN JOURNAL OF PEDIATRICS, cilt.165, sa.5, ss.293-298, 2006 (SCI-Expanded, Scopus)
- Giant axonal neuropathy: clinical and genetic study in six casesJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, cilt.76, sa.6, ss.825-832, 2005 (SCI-Expanded, Scopus)
- Mutations in a gene encoding a novel SH3/TPR domain protein cause autosomal recessive Charcot-Marie-Tooth type 4C neuropathyAMERICAN JOURNAL OF HUMAN GENETICS, cilt.73, sa.5, ss.1106-1119, 2003 (SCI-Expanded, Scopus)
- Four novel thymidine phosphorylase gene mutations in mitochondrial neurogastrointestinal encephalomyopathy syndrome (MNGIE) patientsEUROPEAN JOURNAL OF HUMAN GENETICS, cilt.11, sa.1, ss.102-104, 2003 (SCI-Expanded, Scopus)
- Mutations in GDAP1 - Autosomal recessive CMT with demyelination and axonopathyNEUROLOGY, cilt.59, sa.12, ss.1865-1872, 2002 (SCI-Expanded, Scopus)
- A novel homozygous missense mutation in the myotubularin-related protein 2 gene associated with recessive Charcot-Marie-Tooth disease with irregularly folded myelin sheathsNEUROMUSCULAR DISORDERS, cilt.12, sa.9, ss.869-873, 2002 (SCI-Expanded, Scopus)
- Exercise-induced apoptosis of rat skeletal muscle and the effect of meloxicamRHEUMATOLOGY INTERNATIONAL, cilt.21, sa.4, ss.133-136, 2002 (SCI-Expanded, Scopus)
- Cremaster muscle is not sexually dimorphic, but that from boys with undescended testis reflects alterations related to autonomic innervationJOURNAL OF PEDIATRIC SURGERY, cilt.36, sa.6, ss.877-880, 2001 (SCI-Expanded, Scopus)
- Cremaster muscles obtained from boys with an undescended testis show significant neurological changesBJU INTERNATIONAL, cilt.85, sa.1, ss.116-119, 2000 (SCI-Expanded, Scopus)
- Painful sensory neuropathy: Prospective evaluation using skin biopsyNeurology, cilt.53, sa.8, ss.1641-1647, 1999 (SCI-Expanded, Scopus)
Conference papers 38
- The effect and challenges of nusinersen treatment in adult spinal muscular atrophy patients - preliminary results6th Congress of the European-Academy-of-Neurology (EAN), ELECTR NETWORK, 23 - 26 Mayıs 2020, cilt.27, ss.625, (Özet Bildiri)
- Transthyretin Familial Amyloid Polyneuropathy (TTR-FAP): A Database AnalysisAnnual Meeting of the American-Academy-of-Neurology, Toronto, Kanada, 25 Nisan - 01 Mayıs 2020, cilt.94, (Özet Bildiri)
- Multimodal Assessment Of Intensive Care Unit-Acquired Weakness (ICU-AW) In Severe Acute Stroke Patients2019 PNS Meeting, 22 - 26 Haziran 2019, (Özet Bildiri)
- Nusinersen İlacı İçin Başvuruda Bulunan Spinal Musküler Atrofi Tip 2 ve Tip 3 Tanılı Hastaların ProfiliTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Erişkin Nöromusküler Hastalarda Düşme Öyküsünün AktiviteLimitasyonu ve Gövde Bozukluk Düzeyi ile İlişkisinin İncelenmesiTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Kas Hastalarında Farklı Yüksekliklerden Oturmadan Ayağa Kalkma Sırasında Uyluk Kaslarının Aktivasyon Seviyelerinin İncelenmesiTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Erişkin Kas Hastalarında Fiziksel Aktiviteyi Objektif ve Subjektif Olarak Değerlendiren Yöntemlerin KarşılaştırılmasıTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Erişkin Kas Hastalarında Fiziksel Aktivite ile İlişkili Faktörlerin BelirlenmesiTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Nöroloji Yoğun Bakım Ünitesi'ndeki İnme Hastalarında Yoğun Bakım Ünitesinde Edinilmiş Güçsüzlüğün (YBÜ-EG) Multimodal İncelemesi35. ULUSAL KLİNİK NÖROFİZYOLOJİ EEG-EMG KONGRESİ, Muğla, Türkiye, 3 - 07 Nisan 2019, (Özet Bildiri)
- Differentially Expressed microRNA Profile in Skeletal Muscle Tissue of Sporadic ALS Patients71st Annual Meeting of the American-Academy-of-Neurology (AAN), Pennsylvania, Amerika Birleşik Devletleri, 4 - 10 Mayıs 2019, cilt.92, (Özet Bildiri)
- The expression of epidermal growth factor (EGF) and keratinocyte growth factor (KGF) in skin biopsy of amyotrophic lateral sclerosis patients70th Annual Meeting of the American-Academy-of-Neurology (AAN), Los-Angeles, Şili, 21 - 27 Nisan 2018, cilt.90, (Özet Bildiri)
- Altered Expression of Perineuronal Net Elements in SMN Knockdown Cells50th European-Society-of-Human-Genetics (ESHG) Conference, Copenhagen, Danimarka, 27 - 30 Mayıs 2017, cilt.26, ss.622, (Özet Bildiri)
- Establishment of primary myoblast cell culture from cryoprotected skeletal muscle biopsies22nd International Annual Congress of the World-Muscle-Society (WMS), Saint-Lo, Fransa, 3 - 07 Ekim 2017, cilt.27, (Özet Bildiri)
- VECTOR-BORNE VIRAL INFECTIONS IN GUILLAIN BARRE SYNDROME PATIENTSPeripheral-Nerve-Society Meeting, Sitges, İspanya, 8 - 12 Temmuz 2017, cilt.22, ss.349-350, (Özet Bildiri)
- Acute myopathy in patients who are using short term and low dose systemic glucocorticoids: preliminary findings16th Congress of Internal Medicine, 31 Ağustos - 02 Eylül 2017, (Özet Bildiri)
- Acute myopathy in patients who are using short-term and low-dose systemic glucucorticoids: Preliminary findings16th European Congress of Internal Medicine, 31 Ağustos - 02 Eylül 2017, (Özet Bildiri)
- Desmin Mutation with an ultra rare and unique phenotype: Genome editing for a patient specific zebrafish modelkeystone symposia Rare and Undiagnosed Diseases, Massachusetts, Amerika Birleşik Devletleri, 3 - 05 Ağustos 2017, (Özet Bildiri)
- Recurrent peripheral and central demyelination in a seronegative patientperipheral Nerve Society Meeting, 8 Temmuz - 13 Eylül 2017, (Özet Bildiri)
- Low levels of SMN cause alterations in microtubule associated protein 1b21th Annual Spinal Muscular Atrophy Researcher Meeting, Orlando, Amerika Birleşik Devletleri, 29 Haziran - 02 Temmuz 2017, (Özet Bildiri)
- Modeling of a unique desmin mutaion in zebrafish by using genome editing brings new insights into desmin functionEuropean Human Genetics Conference, 27 - 30 Mayıs 2017, (Özet Bildiri)
- Modeling of a unique desmin mutation in zebrafish by using genome editing brings new insights into desmin functionESHG 2017, 27 - 30 Mayıs 2017, (Özet Bildiri)
- 11 YILLIK MİYASTENİ GRAVİS OLGUSUNDA YENİ GELİŞEN NÖROMİYOTONİ33. Ulusal Klinik Nörofizyoloji EEG-EMG Kongresi, Türkiye, 12 - 16 Nisan 2017, (Özet Bildiri)
- The Histopathological Evaluation of Small Fiber Neuropathy in Patients with Vitamin B12 Deficiency68th Annual Meeting of the American-Academy-of-Neurology (AAN), Vancouver, Kanada, 15 - 21 Nisan 2016, cilt.86, (Özet Bildiri)
- Myastenia Gravis de Velofaringeal Fonksiyonun Araştırılması4. YUTMA BOZUKLUKLARI KONGRESİ, Türkiye, 19 - 21 Kasım 2015, (Özet Bildiri)
- The incidence of Pompe disease in patients with vacuolar myopathy: a pilot study of a tertiary care center1st Congress of the European-Academy-of-Neurology, Berlin, Almanya, 20 - 23 Haziran 2015, cilt.22, ss.623, (Özet Bildiri)
- A novel mutation in the HTRA1 gene in a Turkish family with CARASIL1st Congress of the European-Academy-of-Neurology, Berlin, Almanya, 20 - 23 Haziran 2015, cilt.22, ss.258, (Özet Bildiri)
- The time course of pseudo-conduction blocks in a patient with vasculitic neuropathyJoint Congress of European Neurology, İstanbul, Türkiye, 31 Mayıs - 03 Haziran 2014, cilt.261, (Özet Bildiri)
- Three families with hereditary amyloid polyneuropathy with three different mutationsJoint Congress of European Neurology, İstanbul, Türkiye, 31 Mayıs - 03 Haziran 2014, cilt.261, (Özet Bildiri)
- A novel desmin mutation causes autosomal recessive limb girdle muscular dystrophy without features of myofibrillar myopathy18th International Congress of the World-Muscle-Society (WMS), California, Amerika Birleşik Devletleri, 1 - 05 Ekim 2013, cilt.23, ss.851-852, (Özet Bildiri)
- Inflammatory effect of AbetaPP induced ST6Gal1 secretion from myogenic cell line16th International Congress of the World-Muscle-Society, Algarve, Portekiz, 18 - 22 Ekim 2011, cilt.21, ss.746, (Özet Bildiri)
- MİYASTENİK KRİZ İLE BAŞVURAN HASTALARDA YARDIMCI FOLİKÜLER T HÜCRE (TFH) VE YARDIMCI T HÜCRE 17 (TH17) İLİŞKİLİ SİTOKİNLERİN TEDAVİ ÖNCESİ VE SONRASI DEĞİŞKENLİĞİ
- NUSİNERSEN TEDAVİSİ ALAN ERİŞKİN SPİNAL MUSKÜLER ATROFİ HASTALARINDA İNFLAMASYON VE GLİAL HÜCRE İLİŞKİLİ BİYOBELİRTEÇLERİN TESPİTİ
- Evaluation of the Role of Glial Factors in the Pathogenesis of Spinal Muscular Atrophy
- Serum Cytokines Levels in Patients with Myasthenia Gravis and Their Changes After Treatment
- COVID 19 Pandemisinin Nöromusküler Hastalığa Sahip Erişkin Bireyler Üzerine Etkisi
- MME MUTASYONUNA BAĞLI DEMİYELİNİZAN NÖROPATİ
- A novel ARMS-PCR assay for screening MT-TL1 mutations causing mitochondrial cytopathies
- Inflammatory pan-demyelination syndrome IPANDS of the whole nervous system
Contact
- Department
- Neurology, Adult Hospital
- Languages
- English
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