Patients with recurrent infections, families with child death histories, patients with autoimmune and lymphoproliferative disorders or with primary immunodeficiency that require stem cell transplantation are referred to the unit, and they followed up in the outpatient clinics and services regularly and are treated. A part of the diagnosed patients receive intravascular immunoglobulin (IVIG) treatment in our outpatient clinic on a monthly basis. With the help of molecular activities genetic counseling is also offered to the families of patients with immunodeficiency.
The researches on clinic and laboratory indications, diagnostic molecular tests and treatment approaches for patients with primary immunodeficiency disorders such as T and B stem cell deficiencies, phagocytic system disorders, complement deficiencies, ataxia telangiectasia are carried out in the unit. While the unit has the widest serial in immunodeficiency disorder patient group, it has been observing the greatest patient group of the world in diagnosis of the diseases known ad ataxia telangiectasia.
In the laboratory which includes the sterile culture room in where the immune system functions are defined, and the laboratory of molecular research and HLA, the advanced tests that used in diagnoses of primary immunodeficiency diseases are performed.
HLA antigen studies have been carried out for determining the compliant donors for transplantation patients, since the middle of 1970s.
So many national and international research activities have been carried out in the unit, and it has assumed the leadership in enlightening the molecular pathogeneses of various diseases. "Inherited Immunodeficiency Unit" was established within the scope of TÜBİTAK and within the context of this unit seven projects were supported by TÜBİTAK.
The unit has been making efforts to heighten the awareness of society on primary immunodeficiency disorders. In this regard, it has a role in organizing various regional meetings and courses and once more within this context, established the Pediatric Immunology Unit of Ankara University Faculty of Medicine along with Jeffrey Modell Ankara Center.
Detailed examinations and diagnostic tests are practiced in our department. Procedures of intravascular immunoglobulin, giving blood and other blood products for the patients are performed in the treatment room, within working hours.