Cem Şimşek

Doç. Dr. Cem Şimşek, Hacettepe Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim Dalı’nda öğretim üyesidir. 2013 yılında Hacettepe Üniversitesi Tıp Fakültesi’nden yüksek onur derecesiyle mezun olmuş, 2018 yılında Tıpta Uzmanlık Sınavı’nda (TUS) birincilikle Hacettepe Üniversitesi’nde İç Hastalıkları ihtisasına başlamıştır. 2021 yılında Gastroenteroloji yan dal uzmanlığını tamamlamış ve Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü’nde Temel Cerrahi Araştırmaları alanında doktora (Ph.D.) çalışmalarına devam etmektedir.

1. Artificial intelligence in gastroenterology clinical practice: Scoping review of large language model applicationsYazarkan Y., Sonmez G., ŞİMŞEK C.International Journal of Medical Informatics, cilt.214, 2026 (SCI-Expanded, Scopus)
2. Shifts in liver biopsy indications and histopathological diagnoses: A report from a tertiary care center in TürkiyeDALKILIÇ Y. E., PARLAR Y. E., ŞİMŞEK C., KİKİ Z., DAĞ O., SÖKMENSÜER C., et al.Hepatology Forum, cilt.7, sa.3, ss.262-268, 2026 (Scopus)
3. Comparative Performance of Large Language Models on European Gastroenterology Board-Style Questions: Analysis of Reasoning Versus Non-Reasoning ArchitecturesŞİMŞEK C., Vanek P., Aydinli H., Krivinka J., Lehner M., Schiavone S., et al.Journal of Clinical Medicine, cilt.15, sa.7, 2026 (SCI-Expanded, Scopus)
4. Lack of follow-up in Helicobacter pylori eradication treatment: Results from the European registry on Helicobacter pylori managementCantú-Germano E., Moreira L., Pérez-Aisa Á., Martínez-Domínguez S. J., Voynovan I., Bujanda L., et al.World Journal of Gastroenterology, cilt.32, sa.7, 2026 (SCI-Expanded, Scopus)
5. Higher Doses of Bismuth and Antibiotics Do Not Improve Helicobacter pylori Treatment Effectiveness: Results From the European Registry on Helicobacter pylori ManagementMartínez-Domínguez S. J., Lanas Á., Ceamanos E., Voynovan I., Jonaitis L., Vologzanina L., et al.Clinical Gastroenterology and Hepatology, 2026 (SCI-Expanded, Scopus)
6. Magnets in tiny ducts: magnetic compression anastomosis in the pediatric population — a review of the literature with illustrative casesÜNAL E., Göl M., UYSAL A., ŞİMŞEK C., ÇİFTÇİ T. T., AKINCI D., et al.Pediatric Radiology, 2026 (SCI-Expanded, Scopus)
7. Commercial real-time PCR kit results for the detection of Helicobacter pylori and clarithromycin resistance in stool samplesInal N., Sahin T., BALABAN H. Y., ŞİMŞEK C., Simsek H., Akyon Y.INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, cilt.57, 2025 (SCI-Expanded, Scopus)
8. Evaluating the Role of Artificial Intelligence in Making Clinical Decisions for Treating Acute PancreatitisBALABAN H. Y., ÜÇDAL M., DURAK M. B., ŞİMŞEK C.JOURNAL OF CLINICAL MEDICINE, cilt.14, 2025 (SCI-Expanded, Scopus)
9. Gastroenterology Training and Career in Women: Challenges and OpportunitiesManthopoulou E., Catalan-Serra I., Corsetti M., Nowak A., Perugorria M. J., ŞİMŞEK C., et al.UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, cilt.13, sa.4, ss.650-655, 2025 (SCI-Expanded, Scopus)
10. Ascending the "Hill" of Artificial Intelligence in Upper Gastrointestinal EndoscopyŞİMŞEK C., Parsa N., Kunovsky L.UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, cilt.13, sa.4, ss.510-511, 2025 (SCI-Expanded, Scopus)
11. Endoscopic Retrograde Cholangiopancre atography in Pediatric Population: A Decade-Long Experience from 2 Tertiary CentersBatibay E., Yuksekyayla O., Polat M., Bayhan I., Sevinc M., Dag A., et al.TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.36, sa.5, ss.321-327, 2025 (SCI-Expanded, Scopus, TRDizin)
12. Endoscopic retrograde cholangiopancreatography training conditions, results from a pan-European survey: Between vision and realityHamesch K., Cahyadi O., Dimitriadis S., Hollenbach M., Acedo P., Ayari M., et al.UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, cilt.13, sa.3, ss.474-487, 2025 (SCI-Expanded, Scopus)
13. Astroviruses and celiac disease: a preliminary study into potential environmental triggersPOLAT C., ŞAHİN T., ŞİMŞEK C., TEKİN İ. E., İsrafilov S., SÖKMENSÜER C., et al.Acta Medica, 2025 (TRDizin)
14. Effect of periampullary diverticulum morphology on ERCP cannulation and clinical resultsCagir Y., DURAK M. B., ŞİMŞEK C., YÜKSEL İ.SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, cilt.60, sa.4, ss.292-299, 2025 (SCI-Expanded, Scopus)
15. QUAIDE - Quality assessment of AI preclinical studies in diagnostic endoscopyAntonelli G., Libanio D., De Groof A. J., van der Sommen F., Mascagni P., Sinonquel P., et al.GUT, cilt.74, ss.153-161, 2024 (SCI-Expanded, Scopus)
16. Prospective evaluation of patients with non-cirrhotic portal hypertension: A single-centre studyUcdal M., ŞİMŞEK C., Durak B., BALABAN H. Y.ALIMENTARY PHARMACOLOGY & THERAPEUTICS, cilt.60, sa.10, ss.1487-1488, 2024 (SCI-Expanded, Scopus)
17. Prevalence of Gastroparesis in Patients With Chronic Pancreatitis and Predictive Factors: A Novel Prediction Model Using Supervised Machine LearningRamai D., Pan C., Fellows E., Wang Y., Huang Y., Shah I., et al.AMERICAN JOURNAL OF GASTROENTEROLOGY, sa.10S, 2024 (SCI-Expanded, Scopus)
18. Comparison of ERCP Outcomes and Complication Risk between Elderly and Younger Patients: A Large Single-Center StudyCagir Y., Durak M. B., ŞİMŞEK C., YÜKSEL İ.JOURNAL OF CLINICAL MEDICINE, cilt.13, sa.20, 2024 (SCI-Expanded, Scopus)
19. Specific Oral Manifestations in Adults with Crohn's DiseaseCagir Y., DURAK M. B., ŞİMŞEK C., YÜKSEL İ.JOURNAL OF CLINICAL MEDICINE, cilt.13, sa.13, 2024 (SCI-Expanded, Scopus)
20. The evolution and revolution of artificial intelligence in hepatology: From current applications to future paradigmsŞİMŞEK C.HEPATOLOGY FORUM, cilt.5, sa.3, ss.97-99, 2024 (ESCI, Scopus, TRDizin)
21. Inborn Errors of Immunity in Adults with Autoimmune Liver Diseases.Ayar Ş. N., Aytekin E. S., Şimşek C., Dağ O., Çağdaş D. N., Balaban Y. H.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, cilt.35, sa.7, ss.560-567, 2024 (SCI-Expanded, Scopus, TRDizin)
22. The frequency and clinical significance of antibodies to soluble liver antigen/liver pancreas in autoimmune hepatitis: a prospective single-center studyYüksekyayla O., Kina N., Ulaba A., Emin Ergün M., Batibay E., ŞİMŞEK C., et al.European Journal of Gastroenterology and Hepatology, cilt.36, sa.5, ss.652-656, 2024 (SCI-Expanded, Scopus)
23. Effectiveness of Helicobacter pylori Treatments According to Antibiotic ResistanceBujanda L., Nyssen O. P., Ramos J., Bordin D. S., Tepes B., Perez-Aisa A., et al.American Journal of Gastroenterology, cilt.119, sa.4, ss.646-654, 2024 (SCI-Expanded, Scopus)
24. Commercial Real-Time PCR Kit Results for the Detection of Helicobacter pylori and Clarithromycin Resistance in Stool SamplesBALABAN H. Y., İNAL N., ŞİMŞEK C., ŞİMŞEK H., AKYÖN YILMAZ Y.Research Square, 2024 (Hakemli Dergi)
25. Comparison of normal saline and antiseptic solution effect on the early peristomal infection rates of patients with percutaneous endoscopic gastrostomy tubes: A randomized double-blind study.Akcay K., Ayhan H., Sezer Ceren R. E., Simsek C., Abbasoglu O.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, cilt.38, ss.1343-1353, 2023 (SCI-Expanded, Scopus)
26. Ileocecal valve that cannot be intubated in Crohn’s disease: is this a sign of poor prognosis?Durak M. B., Simsek C., İnan B., Yuksel I.International Journal of Colorectal Disease, cilt.38, sa.1, 2023 (SCI-Expanded, Scopus)
27. Clinical Outcomes of Older Patients with Non-Variceal Upper Gastrointestinal Bleeding Taking Anti-Thrombotic or Non-Steroidal Anti-Inflammatory AgentsDurak M. B., Şimşek C., YÜKSEL İ.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, cilt.34, sa.9, ss.918-924, 2023 (SCI-Expanded, Scopus, TRDizin)
28. Gastroplasty with endoscopic myotomy for the treatment of obesityThompson C. C., Jirapinyo P., Shah R., ŞİMŞEK C.VideoGIE, cilt.8, sa.5, ss.193-195, 2023 (Scopus)
29. Novel single-operator through-the-scope traction device for endoscopic submucosal dissection: Outcomes of a multicenter randomized pilot ex-vivo study in trainees with limited endoscopic submucosal dissection experience (with video)Yang D., Aihara H., Hasan M. K., ŞİMŞEK C., Khan H., Brar T. S., et al.DEN Open, cilt.3, sa.1, 2023 (Scopus)
30. Transcriptomic Analysis of Hepatitis B Infected Liver for Prediction of Hepatocellular CarcinomaKaraoglu D. A., ÜNER M., ŞİMŞEK C., GÜRE A. O., DEMİRKOL CANLI S.Biology, cilt.12, sa.2, 2023 (SCI-Expanded, Scopus)
31. Future Directions for Robotic Endoscopy–Artificial Intelligence (AI), Three-Dimensional (3D) Imaging, and Natural Orifice Transluminal Endoscopic Surgery (NOTES)ŞİMŞEK C., Kaan H. L., Aihara H.Techniques and Innovations in Gastrointestinal Endoscopy, cilt.25, sa.1, ss.95-101, 2023 (ESCI, Scopus)
32. Practice patterns and considerations in liver transplantation from living donors with high BMI: A reviewSamaha C., Chaaban H., ŞİMŞEK C., DANIŞ N., Lin J. S., Gurakar A.Hepatology Forum, cilt.4, sa.3, ss.145-149, 2023 (Scopus, TRDizin)
33. Training in Endoscopic Submucosal Dissection in the United States: The Current ParadigmŞİMŞEK C., Aihara H.Gastrointestinal Endoscopy Clinics of North America, cilt.33, sa.1, ss.41-53, 2023 (Scopus)
34. Magnetic Resonance Imaging Predictors of Hepatocellular Carcinoma Progression and Dropout in Patients in Liver Transplantation Waiting ListBaghdadi A., Luu H. T., Shaghaghi M., Ghadimi M., ŞİMŞEK C., Xu Z., et al.Transplantation Direct, cilt.8, sa.11, 2022 (ESCI, Scopus)
35. Empirical Second-Line Therapy in 5000 Patients of the European Registry on Helicobacter pylori Management (Hp-EuReg)Nyssen O. P., Vaira D., Pérez Aísa Á., Rodrigo L., Castro-Fernandez M., Jonaitis L., et al.Clinical Gastroenterology and Hepatology, cilt.20, sa.10, ss.2243-2257, 2022 (SCI-Expanded, Scopus)
36. Novel articulating through-the-scope traction deviceŞİMŞEK C., Thompson C. C., Alkhateeb K. J., Jofre S. A., Aihara H.VideoGIE, cilt.7, sa.10, ss.353-357, 2022 (Scopus)
37. Characteristics of patients with hepatocellular carcinoma: A multicenter studyGuzelbulut F., KARAOĞULLARINDAN Ü., AKKIZ H., ALTINTAŞ E., DEMİRTAŞ C. Ö., Bahadir O., et al.HEPATOLOGY FORUM, cilt.3, sa.3, ss.71-76, 2022 (ESCI, Scopus, TRDizin)
38. Endoscopic submucosal dissection with ductotomy for the resection of a gastric duplication cyst with a communicating ductŞİMŞEK C., Ryou M., Thompson C. C., Aihara H.VideoGIE, cilt.7, sa.8, ss.280-283, 2022 (Scopus)
39. Hepatitis E Virus Prevalence and Associated Risk Factors in High-Risk Groups: A Cross-Sectional StudyBALABAN H. Y., ASLAN A. T., AKDOĞAN KITTANA F. N., ALP A., DAĞ O., AYAR Ş. N., et al.TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.33, sa.7, ss.615-624, 2022 (SCI-Expanded, Scopus, TRDizin)
40. Practical points that gastrointestinal fellows should know in management of COVID-19ŞAHİN T., ŞİMŞEK C., BALABAN H. Y.WORLD JOURNAL OF CLINICAL CASES, cilt.10, sa.16, ss.5133-5145, 2022 (SCI-Expanded, Scopus)
41. Fecal S100A12 in Takayasu arteritis predicts disease activity and intestinal involvementŞİMŞEK C., Berkan A., Alper S., Abdulsamer E., Levent K., Ali A.RHEUMATOLOGY INTERNATIONAL, cilt.42, sa.4, ss.737-742, 2022 (SCI-Expanded, Scopus)
42. Redetermining the cutoff point of peristomal infection scoring: Methodological researchAyhan H., Akcay K., Olmez Y. N., ŞİMŞEK C., ABBASOĞLU O.JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, cilt.46, sa.2, ss.462-468, 2022 (SCI-Expanded, Scopus)
43. The Classification of Biliary Strictures ın Patients With Right Lobe Liver Transplant Recipients and Its Relation to Traversing the Stricture With a Guidewire.Parlak E., Simsek C., Koksal A. S., Eminler A. T., Unal E., Ciftci T. T., et al.Transplantation, cilt.106, ss.328-336, 2022 (SCI-Expanded, Scopus)
44. An update on usage of high-risk donors in liver transplantationMuhammad H., Zaffar D., Tehreem A., Ting P., ŞİMŞEK C., Turan I., et al.Journal of Clinical Medicine, cilt.11, sa.1, 2022 (SCI-Expanded, Scopus)
45. Transoral outlet reduction: could additional sutures cause more harm?Farha J., Gebran S., Itani M. I., Simsek C., Abbarh S., Lopez A., et al.ENDOSCOPY, cilt.53, sa.10, ss.1059-1064, 2021 (SCI-Expanded, Scopus)
46. Endoscopic sleeve gastroplasty: suturing the gastric fundus does not confer benefitFarha J., McGowan C., Hedjoudje A., Itani M. I., Abbarh S., Simsek C., et al.ENDOSCOPY, cilt.53, sa.07, ss.727-731, 2021 (SCI-Expanded, Scopus)
47. Role of gastrointestinal system on transmission and pathogenesis of SARS-CoV-2ŞİMŞEK C., Erul E., BALABAN H. Y.WORLD JOURNAL OF CLINICAL CASES, cilt.9, sa.20, ss.5427-5434, 2021 (SCI-Expanded, Scopus)
48. Etiology of Cirrhosis in Turkey: A National Cohort StudyYILDIRIM A. E., ÜÇBİLEK E., Oruncu M. B., TURAN İ., DEMİR M., Koksal A., et al.JOURNAL OF HEPATOLOGY, cilt.75, 2021 (SCI-Expanded, Scopus)
49. Adverse Event Profile During the Treatment of Helicobacter pylori: A Real-World Experience of 22,000 Patients From the European Registry on H. pylori Management (Hp-EuReg)Nyssen O. P., Perez-Aisa A., Tepes B., Castro-Fernandez M., Kupcinskas J., Jonaitis L., et al.AMERICAN JOURNAL OF GASTROENTEROLOGY, cilt.116, sa.6, ss.1220-1229, 2021 (SCI-Expanded, Scopus)
50. Artificial intelligence method to predict overall survival of hepatocellular carcinomaŞİMŞEK C., GÜVEN D. C., Sahin T. K., TEKİN İ. E., Sahan O., BALABAN H. Y., et al.Hepatology Forum, cilt.2, sa.2, ss.64-68, 2021 (Scopus)
51. Comprehensive clinicopathologic characteristics of intraabdominal neurogenic tumors: Single institution experience.Simsek C., Uner M., Ozkara F., Akman O., Akyol A., Kav T., et al.World journal of clinical cases, cilt.9, ss.2218-2227, 2021 (SCI-Expanded, Scopus)
52. Artificial Intelligence to Predict Esophageal Varices in Patients with CirrhosisTEKİN İ. E., ŞİMŞEK C., BALABAN H. Y., ŞAHİN T. K.Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, cilt.12, ss.625-629, 2021 (TRDizin)
53. V600E and Non-V600E BRAF Mutations in Colorectal Cancer: Clinicopathologic Correlations in a Single InstitutionŞİMŞEK C., LAÇİN Ş., Ece E., YALÇIN Ş.UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, cilt.31, sa.1, ss.43-49, 2021 (SCI-Expanded, Scopus, TRDizin)
54. Lack of Awareness of Hepatitis B Screening and Vaccination in High-Risk Groups.Balaban H. Y., Aslan A. T., Ayar Ş. N., DaĞ O., Alp A., ŞİmŞek C., et al.Turkish journal of medical sciences, cilt.51, ss.1229-1233, 2021 (SCI-Expanded, Scopus, TRDizin)
55. Feasibility of telehealth in the management of autoimmune hepatitis before and during the COVID-19 pandemicEfe C., ŞİMŞEK C., Batibay E., Caliskan A. R., Wahlin S.EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, cilt.14, sa.12, ss.1215-1219, 2020 (SCI-Expanded, Scopus)
56. Anatomical Configuration of the Stomach Post-Endoscopic Sleeve Gastroplasty (ESG)-What Are the Sutures Doing?Runge T. M., Yang J., Fayad L., Itani M. I., Dunlap M., Koller K., et al.OBESITY SURGERY, cilt.30, sa.5, ss.2056-2060, 2020 (SCI-Expanded, Scopus)
57. Gut microbiota and cancer immunotherapy: prognostic and therapeutic implicationsGÜVEN D. C., AKTAŞ B. Y., ŞİMŞEK C., AKSOY S.FUTURE ONCOLOGY, cilt.16, sa.9, ss.497-506, 2020 (SCI-Expanded, Scopus)
58. Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypassFayad L., Trindade A. J., Benias P. C., Simsek C., Raad M., Badurdeen D., et al.ENDOSCOPY, cilt.52, sa.3, ss.227-230, 2020 (SCI-Expanded, Scopus)
59. Considering the first randomized trial of peroral endoscopic myotomy versus surgical myotomy for achalasiaŞİMŞEK C.TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.31, sa.2, ss.190-192, 2020 (SCI-Expanded, Scopus, TRDizin)
60. Update on liver transplantation-newer aspectsMetin O., ŞİMŞEK C., Gurakar A.TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.50, ss.1642-1650, 2020 (SCI-Expanded, Scopus, TRDizin)

All 75 on AVESİS →

1. ENDOSCOPIC MANAGEMENT OF SLEEVE STENOSIS AFTER LAPAROSCOPIC SLEEVE GASTRECTOMY: A 10-YEAR RETROSPECTIVE ANALYSIS OF OUTCOMES, EFFICACY, AND SAFETYSchuster K., Simsek C., Thompson C.Digestive Disease Week (DDW), Washington, Kiribati, 18 - 21 Mayıs 2024, (Özet Bildiri)
2. Hepatitis B virus screening and immunization rates in special risk groups.BALABAN H. Y., ASLAN A. T., AKDOĞAN F. N., ALP A., DAĞ O., AYAR Ş. N., et al.World Congress of Gastroenterology 2019, 21 - 24 Eylül 2019, (Özet Bildiri)
3. Hepatitis E virus epidemiology of patients with chronic hepatitis C in TurkeyBALABAN H. Y., ASLAN A. T., AKDOĞAN F. N., ALP A., DAĞ O., AYAR Ş. N., et al.World Congress of Gastroenterology 2019, 21 - 24 Eylül 2019, (Özet Bildiri)
4. Sepsis İç hastalıkları servislerindeki en önemli mortalite nedeniAkktaş B. Y., ÇALIK BAŞARAN N., BÖLEK E. Ç., ŞENER Y. Z., Ceylan S., YEKEDÜZ E., et al.17. Ulusal İç Hastalıkları Kongresi, Antalya, Türkiye, 14 - 18 Ekim 2015, ss.105
5. Üniversite Öğrencilerinde Karaciğer Hastalıklarına Yönelik Damgalayıcı TutumlarBALABAN H. Y., TAŞKESEN İ., TAŞKESEN B., güniz Dogan b., ŞİMŞEK C., PARLAR Y. E.
6. Fonksiyonel Kabızlıkta Abdominal Masaj ile Birlikte Aerobik Egzersiz Eğitiminin Etkileri: Randomize Kontrollü ÇalışmaDOĞAN İ. G., BALABAN H. Y., AKBAYRAK T., ŞİMŞEK C., ÖZGÜL S.
7. Karaciğer Sağlığı Bilgi ve Farkındalık DüzeyiBALABAN H. Y., TAŞKESEN İ., ÇAKMAK M. F., güniz Dogan b., ŞİMŞEK C.
8. MULTI-AGENT LLM APPROACH VERSUS SINGLE MODEL IN THE MANAGEMENT OF NON-VARICEAL UPPER GASTROINTESTINAL BLEEDINGBALABAN H. Y., ŞİMŞEK C., DURAK M. B., ÜÇDAL M.
9. ROLE OF NUCLEAR RECEPTOR COACTIVATOR 4 (NCOA4) GENE VARIANTS IN METABOLIC HYPERFERRITINEMIA OBSERVED IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS (MASH)BALABAN H. Y., ÜÇDAL M., ŞİMŞEK C., BURUŞ A., ÇELTİKÇİ B.
10. Fonksiyonel Kabızlıkta Abdominal Masaj ile Birlikte Aerobik Egzersiz Eğitiminin Etkileri: Randomize Kontrollü ÇalışmaDoğan İ. G., ATABEY GERLEGİZ E. N., AKBAYRAK T., BALABAN H. Y., ŞİMŞEK C., ATAY B., et al.

1. Kolorektoanal Problemlerde Farmakolojik TedaviBALABAN H. Y., ŞİMŞEK C."Multidisipliner Balış Temeli" ile Pelvik Sağlıkta Fizyoterapi ve Rehabilitasyon, Türkan Albayrak, Serap özgül, Ceren Gürşen, Editör, Hedef Yayıncılık ve Mühendislik, Ankara, ss.249-258, 2023
2. PATOFİZYOLOJİNİN TEMELLERİDURUSU TANRIÖVER M., SARI A., EŞME M., KOÇ YILDIRIM S., YILDIRIM M. Ş., BÖLEK E. Ç., et al.PALME YAYINCILIK, 2017