Begüm Kocatürk

2008 yılında Bilkent Üniversitesi Moleküler Biyoloji ve Genetik Bölümü’nden başarı bursu kazanarak yüksek şeref listesinde mezun olmuştur. Doktorasını Hollanda Leiden Üniversitesi’nde tamamlamış ve pıhtılaşma faktörlerinin meme kanseri gelişiminde etkilerini araştırmıştır. Çalışmalarına doktora sonrası araştırmacı olarak Bilkent Üniversitesi UNAM’da devam etmiş ve Endoplazmik Retikulum Stresin ateroskleroz gelişimindeki etkilerini incelemiştir. Fulbright doktora sonrası araştırmacı bursunu kazanarak Cedars Sinai Tıp Merkezi’nde Kawasaki vaskülitinin etiyolojisini anlamak adına çalışmalarda bulunmuştur. 2020 yılından beri Hacettepe Üniversitesi Temel Onkoloji Anabilim Dalı’nda öğretim üyesi olarak görev yapmaktadır.

1. In silico analysis reveals PRDX4 as a prognostic and oncogenic marker in renal papillary cell carcinomaKOCATÜRK B.Gene, cilt.859, ss.147201, 2023 (SCI-Expanded, Scopus)
2. Identification of thioredoxin domain containing family members' expression pattern and prognostic value in diffuse gliomas via in silico analysisKOCATÜRK B.CANCER MEDICINE, cilt.12, sa.3, ss.3830-3844, 2023 (SCI-Expanded, Scopus)
3. Editorial: Recent advances in pediatric inflammatory diseasesKOCATÜRK B., ÖZMEN F., Arditi M., ÖZEN S.Frontiers in Pediatrics, cilt.11, 2023 (SCI-Expanded, Scopus)
4. MicroRNA-223 Regulates the Development of Cardiovascular Lesions in LCWE-Induced Murine Kawasaki Disease Vasculitis by Repressing the NLRP3 InflammasomeMaruyama D., Kocaturk B., Lee Y., Abe M., Lane M., Moreira D., et al.FRONTIERS IN PEDIATRICS, cilt.9, 2021 (SCI-Expanded, Scopus)
5. Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growthHamid S. M., Citir M., Terzi E. M., Cimen I., Yildirim Z., Dogan A. E., et al.EMBO REPORTS, cilt.21, 2020 (SCI-Expanded, Scopus)
6. Interleukin-1 Beta-Mediated Sex Differences in Kawasaki Disease Vasculitis Development and Response to TreatmentPorritt R. A., Markman J. L., Maruyama D., Kocaturk B., Chen S., Lehman T. J. A., et al.ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, cilt.40, sa.3, ss.802-818, 2020 (SCI-Expanded, Scopus)
7. Intercepting the Lipid-Induced Integrated Stress Response Reduces AtherosclerosisOnat U. I., Yildirim A. D., Tufanli O., Cimen I., Kocaturk B., Veli Z., et al.JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, cilt.73, sa.10, ss.1149-1169, 2019 (SCI-Expanded, Scopus)
8. Targeting IRE1 with small molecules counteracts progression of atherosclerosisTufanli O., Akillilar P. T., Acosta-Alvear D., Kocaturk B., Onat U. I., Hamid S. M., et al.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, cilt.114, sa.8, 2017 (SCI-Expanded, Scopus)
9. Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activationCimen I., Kocaturk B., Koyuncu S., Tufanli O., Onat U. I., Yildirim A. D., et al.SCIENCE TRANSLATIONAL MEDICINE, cilt.8, sa.358, 2016 (SCI-Expanded, Scopus)
10. Alternatively spliced tissue factor synergizes with the estrogen receptor pathway in promoting breast cancer progressionKocaturk B., Tieken C., Vreeken D., Unlu B., Engels C. C., de Kruijf E. M., et al.JOURNAL OF THROMBOSIS AND HAEMOSTASIS, cilt.13, sa.9, ss.1683-1693, 2015 (SCI-Expanded, Scopus)
11. Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor GrowthKocaturk B., Versteeg H. H.JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, sa.96, 2015 (SCI-Expanded, Scopus)
12. Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinomaUnruh D., Turner K., Srinivasan R., Kocaturk B., Qi X., Chu Z., et al.INTERNATIONAL JOURNAL OF CANCER, cilt.134, sa.1, ss.9-20, 2014 (SCI-Expanded, Scopus)
13. Alternatively spliced tissue factor promotes breast cancer growth in a beta 1 integrin-dependent mannerKocaturk B., Van den Berg Y. W., Tiekena C., Mieog J. S. D., de Kruijf E. M., Engels C. C., et al.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, cilt.110, sa.28, ss.11517-11522, 2013 (SCI-Expanded, Scopus)
14. Tissue factor-integrin interactions in cancer and thrombosis: every Jack has his JillKocaturk B., Versteeg H. H.JOURNAL OF THROMBOSIS AND HAEMOSTASIS, cilt.11, ss.285-293, 2013 (SCI-Expanded, Scopus)
15. Tissue factor isoforms in cancer and coagulation: May the best isoform winKocaturk B., Versteeg H. H.THROMBOSIS RESEARCH, cilt.129, 2012 (SCI-Expanded, Scopus)
16. Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factorvan den Hengel L. G., Kocaturk B., Reitsma P. H., Ruf W., Versteeg H. H.BLOOD, cilt.118, sa.12, ss.3446-3448, 2011 (SCI-Expanded, Scopus)

1. Complement C3 deficiency exacerbates development of cardiovascular lesions in the LCWE-induced Kawasaki Disease VasculitisKOCATÜRK B., Lee Y., moreira d., lane m., Noval R. M., Arditi M.Immunology 2020, 8 - 12 Mayıs 2020
2. A bioactive lipid named Palmitoleate inhibits atherosclerosis via downregulation of ER stress and inflammasome activation.KOCATÜRK B., Çimen İ., Tufanlı Ö., Koyuncu S., Apaydın O., Onat U. İ., et al.Hacettepe 2nd lipid research workshop (HULİPAG), Türkiye, 07 Ekim 2017
3. Nutritional modification of endoplasmic reticulum stress and inflammasome activity by a bioactive lipokine prevents atherosclerosisKocaturk B., Cimen I., Tufanli O., Koyuncu S., Apaydin O., Onat U. I., et al.41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.25, (Özet Bildiri)
4. Alternatively spliced tissue factor triggers breast tumor growthKocaturk B., Tieken C., Reitsma P. H., Bogdanov V. Y., Versteeg H. H.6th International Conference on Thrombosis and Hemostasis Issues in Cancer, Bergamo, İtalya, 20 - 22 Nisan 2012, cilt.129, (Özet Bildiri)
5. Blocking Tissue Factor signaling in breast cancer inhibits tumor metastasisUnlu B., Kocaturk B., Ruf W., Versteeg H. H.
6. Alternatively spliced Tissue Factor fuels breast cancer growth by binding to a non-canonical site on beta1 integrinsKOCATÜRK B., van den berg Y. W., Tieken C., Kuppen P. J., ruf w., Reitsma P. H., et al.
7. Differential localization of full length tissue factor and alternatively spliced tissue factor in breast cancer cellsKOCATÜRK B., van den berg Y. W., Reitsma P. H., Bogdanov V. Y., Versteeg H. H.