About
Biyografi:
2016-… Klinik Araştırmalar Birimi Sorumlusu (Hacettepe Üniversitesi Hastaneleri)
2020-2023 – Müdür Yardımcısı (Hacettepe Üniversitesi Kanser Enstitüsü)
2016 – Profesör Doktor (Hacettepe Üniversitesi Kanser Enstitüsü)
2005 – Doçent Doktor (Hacettepe Üniversitesi Kanser Enstitüsü)
2001 – Tıbbi Onkoloji Uzmanı
1998 – İç Hastalıkları Uzmanı
1992 – Tıp Doktoru
تدريب
- 2009Kanser Epidemiyoloji Yüksek Lisans derecesiKanser Epidemiyoloji Yüksek Lisans derecesi
- 2002-2004(Gustave Roussy Enstitüsü, Fransa)Avrupa Kanser Klinik Araştırmaları Diploması
- Tıp Fakültesi (Tıbbi Onkoloji uzmanı )Hacettepe Üniversitesi
- 1998Tıp Fakültesi (İç Hastalıkları uzmanı )Hacettepe Üniversitesi
- 1192Tıp Fakültesi / İngilizce (Tıp Doktoru)Hacettepe Üniversitesi
- 1986Ankara Fen Lisesi
Expertise
Publications
Source: Hacettepe University academic database (AVESİS) · All publications (135) ↗
Articles 117
- Baseline vitamin D status and clinical outcomes in advanced non-small cell lung cancer patients treated with nivolumabScientific Reports, cilt.16, sa.1, 2026 (SCI-Expanded, Scopus)
- The prognostic significance of early changes in the lung immune prognostic index in patients treated with immunotherapy for advanced-stage lung cancerDiscover Oncology, cilt.17, sa.1, 2026 (SCI-Expanded, Scopus)
- Comparison of flat-dose versus weight-based dose nivolumab treatment in NSCLC patientsScientific Reports, cilt.16, sa.1, 2026 (SCI-Expanded, Scopus)
- Baseline serum folic acid as a prognostic biomarker in metastatic renal cell carcinoma treated with targeted therapyDiscover Oncology, cilt.17, sa.1, 2026 (SCI-Expanded, Scopus)
- Prognostic value of the Scottish Inflammatory Prognostic Score in advanced NSCLC treated with second-line nivolumabDiscover Oncology, cilt.17, sa.1, 2026 (SCI-Expanded, Scopus)
- Baseline and three-month De Ritis ratio and gamma-glutamyltransferase as prognostic biomarkers in metastatic renal cell carcinoma treated with targeted therapyScientific Reports, cilt.16, sa.1, 2026 (SCI-Expanded, Scopus)
- SKYSCRAPER-01: Tiragolumab in Combination With Atezolizumab in Previously Untreated PD-L1–High, Locally Advanced, Unresectable or Metastatic Non–Small Cell Lung CancerJournal of Clinical Oncology, cilt.44, sa.25, 2026 (SCI-Expanded, Scopus)
- Association of Cabazitaxel Treatment Beyond 10 Cycles with Survival Outcomes in Metastatic Castration-Resistant Prostate Cancer: A Retrospective 8-Month Landmark AnalysisJournal of Clinical Medicine, cilt.15, sa.18, 2026 (SCI-Expanded, Scopus)
- Clinical Characteristics and Survival Outcomes of a Clinically Defined Treatment-Emergent Neuroendocrine/Aggressive-Variant Prostate Cancer Phenotype: A Retrospective StudyMedicina (Lithuania), cilt.62, sa.9, 2026 (SCI-Expanded, Scopus)
- Prognostic Value of the Modified Glasgow Prognostic Score in Patients with Metastatic Renal Cell Carcinoma Receiving Nivolumab as Second-Line Therapy: A Multicentre Retrospective Cohort StudyMedicina (Kaunas, Lithuania), cilt.62, sa.9, 2026 (SCI-Expanded, Scopus)
- Real-World Efficacy and Safety of Frontline Enfortumab Vedotin Plus Pembrolizumab in Metastatic Urothelial Carcinoma: A Multicenter Study and Review of the LiteratureClinical Genitourinary Cancer, cilt.24, sa.5, 2026 (SCI-Expanded, Scopus)
- Serum Vitamin D Levels as a Prognostic Biomarker in Patients Receiving Immune Checkpoint InhibitorsJournal of Oncological Science, cilt.12, sa.1, ss.1-8, 2026 (Scopus, TRDizin)
- Comparison of 6 cycles with 4 cycles of chemotherapy and atezolizumab in the first-line treatment of ES-SCLC: a retrospective multicenter analysisOncologist, cilt.31, sa.4, 2026 (SCI-Expanded, Scopus)
- High AST and the presence of liver metastases may guide for the need for FDG PET in advanced prostate cancer patientsUrologic Oncology: Seminars and Original Investigations, cilt.44, sa.4, 2026 (SCI-Expanded, Scopus)
- Survival Outcomes After irAE-Related Nivolumab Discontinuation in mNSCLC: A Multicenter StudyJournal of Clinical Medicine, cilt.15, sa.8, 2026 (SCI-Expanded, Scopus)
- Real-world comparison of cabozantinib and sunitinib in advanced non-clear cell renal cell carcinoma: A multicenter study by the Turkish Oncology GroupInternational Journal of Cancer, cilt.158, sa.4, ss.1067-1079, 2026 (SCI-Expanded, Scopus)
- Prognostic factors in avelumab maintenance therapy for metastatic urothelial carcinomaImmunotherapy, 2026 (SCI-Expanded, Scopus)
- Prognostic Significance of C-PLAN Index in Patients Treated with Immunotherapy for Non-Small-Cell Lung CancerJournal of Clinical Medicine, cilt.15, sa.2, 2026 (SCI-Expanded, Scopus)
- Real-world testing practices, treatment patterns, and outcomes of tyrosine kinase inhibitors (TKIs) in epidermal growth factor receptor-mutated advanced/metastatic non-small cell lung cancer: An international studyCancer Treatment and Research Communications, cilt.48, 2026 (ESCI, Scopus)
- Impact of renin–angiotensin system inhibitors on the clinical outcomes of nivolumab therapy in metastatic non–small cell lung cancerExpert Review of Anticancer Therapy, cilt.26, sa.7, ss.929-936, 2026 (SCI-Expanded, Scopus)
- The lactate dehydrogenase-to-albumin ratio is a prognostic biomarker in extensive-stage small-cell lung cancerActa Medica, cilt.56, sa.3, ss.186-198, 2025 (TRDizin)
- Early Changes in Volumetric Body Composition Parameters Predict Survival Outcomes in Patients with Metastatic Renal Cell Carcinoma Treated with Targeted TherapyJOURNAL OF CLINICAL MEDICINE, cilt.14, sa.9, 2025 (SCI-Expanded, Scopus)
- Comparative Analysis of Prognostic Potential of Pretreatment Blood-Based Biomarkers in Metastatic Bladder Cancer: Modified Glasgow Prognostic ScoreJOURNAL OF CLINICAL MEDICINE, cilt.14, sa.6, 2025 (SCI-Expanded, Scopus)
- Efficacy and Clinical Outcomes of Crizotinib in Patients with ROS1-Rearranged NSCLC: A Multicenter StudyMEDICINA-LITHUANIA, cilt.61, sa.3, 2025 (SCI-Expanded, Scopus)
- Avelumab maintenance in patients with metastatic urothelial carcinoma in a real-life expanded-access program (EAP).JOURNAL OF CLINICAL ONCOLOGY, sa.5_SUPPL, 2025 (SCI-Expanded, Scopus)
- The association between HALP score and survival in patients treated with immune checkpoint inhibitorsEXPERT REVIEW OF ANTICANCER THERAPY, cilt.25, sa.1, ss.81-89, 2025 (SCI-Expanded, Scopus)
- Comparison of the efficacy of sunitinib and pazopanib in patients with advanced non-clear renal cell carcinomaJOURNAL OF CHEMOTHERAPY, cilt.37, sa.6, ss.551-562, 2025 (SCI-Expanded, Scopus)
- The association between blood sodium levels and survival in patients treated with immune checkpoint inhibitorsEXPERT REVIEW OF MOLECULAR DIAGNOSTICS, cilt.25, sa.4, ss.129-137, 2025 (SCI-Expanded, Scopus)
- Association Between Baseline and Changes in Early Neutrophil-to-Lymphocyte Ratio on Survival in Patients with Metastatic Bladder Carcinoma Treated with ImmunotherapyMEDICINA-LITHUANIA, cilt.60, sa.12, 2024 (SCI-Expanded, Scopus)
- Immune Checkpoint Blockade Therapies Efficacy and Toxicity in Patients With Impaired Renal Function in Metastatic Bladder CancerCLINICAL GENITOURINARY CANCER, cilt.22, sa.6, 2024 (SCI-Expanded, Scopus)
- Bi-weekly irinotecan is an effective and convenient regimen in the treatment of relapsed or refractory small cell lung cancerBMC CANCER, cilt.24, sa.1, 2024 (SCI-Expanded, Scopus)
- Efficacy of Systemic Treatments in Patients With Metastatic Lung Invasive Mucinous AdenocarcinomaCLINICAL LUNG CANCER, sa.7, 2024 (SCI-Expanded, Scopus)
- Objective Response Rate is a Surrogate Marker for Long-Term Overall Survival in Metastatic Urothelial Carcinoma Patients Treated With Immune Checkpoint InhibitorsCLINICAL GENITOURINARY CANCER, cilt.22, sa.5, 2024 (SCI-Expanded, Scopus)
- Impact of opioid analgesics on survival in cancer patients receiving immune checkpoint inhibitorsSUPPORTIVE CARE IN CANCER, cilt.32, sa.7, 2024 (SCI-Expanded, Scopus)
- A randomized, open-label, phase 3 trial of pembrolizumab plus epacadostat versus sunitinib or pazopanib as first-line treatment for metastatic renal cell carcinoma (KEYNOTE-679/ECHO-302)BMC CANCER, cilt.23, sa.SUPPL 1, 2024 (SCI-Expanded, Scopus)
- Adrenocortical Cancer in the Real World: A Comprehensive Analysis of Clinical Features and Management from the Turkish Oncology Group (TOG)Clinical Genitourinary Cancer, cilt.22, sa.3, 2024 (SCI-Expanded, Scopus)
- A multicenter, retrospective archive study of radiological and clinical features of ALK-positive non-small cell lung cancer patients and crizotinib efficacyMEDICINE, cilt.103, sa.21, 2024 (SCI-Expanded, Scopus)
- The efficacy of immunotherapy and chemoimmunotherapy in patients with advanced rare tumors: A Turkish oncology group (TOG) studyCancer Medicine, cilt.13, sa.1, 2024 (SCI-Expanded, Scopus)
- Is there any prognostic significance in pleural involvement and/or effusion in patients with ALK-positive NSCLC?Journal of Cancer Research and Clinical Oncology, cilt.149, sa.14, ss.13271-13277, 2023 (SCI-Expanded, Scopus)
- Mean Platelet Volume to Lymphocyte Ratio: A New Biomarker Predicting Response in Patients with Solid Tumors Treated with NivolumabJournal of Immunotherapy and Precision Oncology, cilt.6, sa.4, ss.170-176, 2023 (Scopus)
- The incidence and risk factors for acute kidney injury in patients treated with immune checkpoint inhibitorsAnti-Cancer Drugs, cilt.34, sa.6, ss.783-790, 2023 (SCI-Expanded, Scopus)
- The benefit of treatment beyond progression with immune checkpoint inhibitors: a multi-center retrospective cohort studyJOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, cilt.149, sa.7, ss.3599-3606, 2023 (SCI-Expanded, Scopus)
- Five-Year Outcome and Safety in Patients Treated With Immune Checkpoint Blockade Therapies for Urothelial Carcinoma: Experience From Real-World Clinical PracticeClinical Genitourinary Cancer, cilt.21, sa.3, ss.334-341, 2023 (SCI-Expanded, Scopus)
- Immunogenicity of two doses of inactive COVID-19 vaccine and third booster dose mRNA vaccine in patients with cancer receiving active systemic therapyINTERNATIONAL JOURNAL OF CANCER, cilt.152, ss.679-685, 2023 (SCI-Expanded, Scopus)
- NEPTUNE: Phase 3 Study of First-Line Durvalumab Plus Tremelimumab in Patients With Metastatic NSCLCJournal of Thoracic Oncology, cilt.18, sa.1, ss.106-119, 2023 (SCI-Expanded, Scopus)
- Blood Based Biomarkers as Predictive Factors for Hyperprogressive DiseaseJOURNAL OF CLINICAL MEDICINE, cilt.11, sa.17, 2022 (SCI-Expanded, Scopus)
- The Association between Early Changes in Neutrophil-Lymphocyte Ratio and Survival in Patients Treated with ImmunotherapyJOURNAL OF CLINICAL MEDICINE, cilt.11, sa.15, 2022 (SCI-Expanded, Scopus)
- The burden of polypharmacy and drug-drug interactions in older cancer patients treated with immunotherapyJOURNAL OF ONCOLOGY PHARMACY PRACTICE, cilt.28, sa.4, ss.785-793, 2022 (SCI-Expanded, Scopus)
- Effect of docetaxel (D) use on survival outcomes in patients with metastatic castration-sensitive prostate cancer (mCSPC) treated with novel hormonal therapies (NHTs): A meta-analysis.JOURNAL OF CLINICAL ONCOLOGY, cilt.40, sa.16, 2022 (SCI-Expanded, Scopus)
- Phase II study of afatinib plus pembrolizumab in patients with squamous cell carcinoma of the lung following progression during or after first-line chemotherapy (LUX-Lung-IO)& nbsp;LUNG CANCER, cilt.166, ss.107-113, 2022 (SCI-Expanded, Scopus)
- Response to first-line chemotherapy regimen is associated with efficacy of immune checkpoint blockade therapies in patients with metastatic urothelial carcinomaINTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, cilt.27, sa.3, ss.585-591, 2022 (SCI-Expanded, Scopus)
- Everolimus and/or Nivolumab-Associated Cytomegalovirus Colitis in a Patient with Metastatic Renal Cell CarcinomaEURASIAN JOURNAL OF MEDICINE, cilt.54, sa.1, ss.77-79, 2022 (ESCI, Scopus, TRDizin)
- Long-term outcome and safety in patients treated with immune checkpoint blockade therapies for urothelial carcinoma: Experience from real-world clinical practice.JOURNAL OF CLINICAL ONCOLOGY, cilt.40, sa.6, 2022 (SCI-Expanded, Scopus)
- Differences between Hyperprogressive Disease and Progressive Disease in Patients Receiving ImmunotherapyEURASIAN JOURNAL OF MEDICINE AND ONCOLOGY, cilt.6, sa.1, ss.59-63, 2022 (ESCI, TRDizin)
- The association between antibiotic use and survival in renal cell carcinoma patients treated with immunotherapy: a multi-center studyCURRENT PROBLEMS IN CANCER, cilt.45, sa.6, 2021 (SCI-Expanded, Scopus)
- The Predictive Value of Red Blood Cell Distribution Width for Survival Outcomes of Metastatic Renal Cell Carcinoma Patients Treated with Targeted TherapyNUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, cilt.73, sa.10, ss.1957-1963, 2021 (SCI-Expanded, Scopus)
- Should Protocols Specific to Histologic Subtypes Be Applied in the Follow-Up of NSCLC?JOURNAL OF THORACIC ONCOLOGY, cilt.16, sa.10, 2021 (SCI-Expanded, Scopus)
- Atezolizumab in Patients with Metastatic Urothelial Carcinoma Who Have Progressed After First-line Chemotherapy: Results of Real-life ExperiencesEUROPEAN UROLOGY FOCUS, cilt.7, sa.5, ss.1061-1066, 2021 (SCI-Expanded, Scopus)
- Lower prognostic nutritional index is associated with poorer survival in patients receiving immune-checkpoint inhibitorsBIOMARKERS IN MEDICINE, cilt.15, sa.13, ss.1123-1130, 2021 (SCI-Expanded, Scopus)
- Poorer baseline performance status is associated with increased thromboembolism risk in metastatic cancer patients treated with immunotherapySUPPORTIVE CARE IN CANCER, cilt.29, sa.9, ss.5417-5423, 2021 (SCI-Expanded, Scopus)
Conference papers 17
- Efficacy of systemic treatments in patients with metastatic lung invasive mucinous adenocarcinomaSpecial Clinical Science Symposia, ELECTR NETWORK, 29 Mayıs 2024, (Özet Bildiri)
- Atezolizumab in patients with metastatic urothelial carcinoma who have progressed after first-line chemotherapy: Results of real-life experienceGenitourinary Cancers Symposium of the American-Society-of-Clinical-Oncology (ASCO), San-Francisco, Kostarika, 13 - 15 Şubat 2020, cilt.38, (Özet Bildiri)
- İki olgu nedeniyle Nivolimumaba bağlı akciğer toksisitesiUlusal Akciğer Sağlığı Kongresi, Türkiye, 14 - 18 Mart 2018, (Özet Bildiri)
- Brain Tissue Follow-up Using Dynamic Susceptibility Contrast-Enhanced and Dynamic Contrast-Enhanced Perfusion Magnetic Resonance Imaging on Lesions Categorized by Apparent Diffusion Coefficient Values in GlioblastomaRadiology Society of North America, 26 Kasım - 01 Aralık 2017, (Özet Bildiri)
- Efficiency of a psychoeducational Intervention for smoking cessation in a specialized cessation clinic2017 World Congress of Psycho-Oncology, 14 - 18 Ağustos 2017, (Özet Bildiri)
- Tirozin Kinaz İnhibitörü Kaynaklı Tiroid Fonksiyon Bozukluğu18. ULUSAL İÇ HASTALIKLARI KONGRESİ, Türkiye, 12 - 16 Ekim 2016, (Özet Bildiri)
- Anti TNF treatment may induce EBV reactivation in RA patients A clue for increased risk of lymphomaAnnual European Congress of Rheumatology (EULAR 2006), 21 - 24 Haziran 2006, (Tam Metin Bildiri)
- Addition of rituximab to chop does not increase the risk of cardiotoxicity in patients with non-Hodgkin's lymphoma30th Congress of the European-Society-for-Medical-Oncology, İstanbul, Türkiye, 29 Eylül - 03 Ekim 2006, cilt.17, ss.202, (Özet Bildiri)
- An open study of clarithromycin in the treatment of pneumonia due to Streptococcus pneumoniae3rd International Conference on the Macrolides, Azalides, and Streptogramins, Lisbon, Portekiz, 24 - 26 Ocak 1996, cilt.21, ss.429-431, (Tam Metin Bildiri)
- BİR ÜNİVERSİTENİN SİGARA BIRAKMA ÜNİTESİNE BAŞVURANLARIN ÖZELLİKLERİ VE SİGARA BIRAKMA OLASILIKLARI
- TRANSCULTURAL ADAPTATION OF EORTC-QLQ-CR29 SCALE INTO TURKISH, AND ASSESSMENT OF VALIDITY ANDRELIABILITY IN TURKISH PATIENTS WITH COLORECTAL CANCER
- EFFECTS OF CANCER TYPES ON LOCAL AND OUT-OF-CITY ADMISSIONS FOR MEDICAL CARE
- Metastatik kastrasyona dirençli prostat kanser hastalarında kabazitakselin güvenlik verileri: Kabazitaksel Türkiye insani amaçlı ilaca erişim programı sonuçları
- Smoker relatives of inpatients: A reasonable but heterogeneous target population for smoking cessation program
- Using geographical information systems to describe quality of life as a function of distance in cancer patients
- Factors that affect the suitability of cancer patients for clinical drug trials in Turkey: Final analysis of a multicenter study.
- Temporal changes in the survival of metastatic renal cell cancer patients and the impact of targeted agents: Single center experience
Kitaplar 1
- Kastrasyona dirençli prostat kanseri tedavisiÜroonkoloji Kitabı, , Editör, Nobel, 2018
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- Preventive Oncology, مستشفى الأورام
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